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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

SCHEDULE 13D

Under the Securities Exchange Act of 1934
(Amendment No. 3 )*

Sequenom, Inc.
(Name of Issuer)
Common Stock, par value $0.001 per share
(Title of Class of Securities)
817337108
(CUSIP Number)
Kevin M. Royer, Esq.
Siemens Corporation
153 East 53 Street, 56th Floor
New York, NY 10022
(212) 258-4151
(Name, Address and Telephone Number of Person Authorized to
Receive Notices and Communications)
May 30, 2008
(Date of Event which Requires Filing of this Statement)

If the filing person has previously filed a statement on Schedule 13G to report the acquisition which is the subject of this Schedule 13D, and is filing this schedule because of §§ 240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the following box. o

Note: Schedules filed in paper format shall include a signed original and five copies of the schedule, including all exhibits. See §240.13d-7(b) for other parties to whom copies are to be sent.

* The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

Persons who respond to the collection of information contained in this form are not
required to respond unless the form displays a currently valid OMB control number.


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SCHEDULE 13D

                     
CUSIP No.
 
859823106 
 
           
1   NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

Siemens Venture Capital GmbH
     
     
2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

  (a)   o 
  (b)   þ 
     
3    
  SEC USE ONLY
   
     
4    
  SOURCE OF FUNDS OO
 
     
5    
  CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) or 2(e)
  o
     
6  
  CITIZENSHIP OR PLACE OF ORGANIZATION Federal Republic of Germany
 
       
  7    
  SOLE VOTING POWER 1,852,972
NUMBER OF    
       
SHARES 8    
BENEFICIALLY SHARED VOTING POWER 0
OWNED BY    
       
EACH 9    
REPORTING SOLE DISPOSITIVE POWER 1,852,972
PERSON    
       
WITH 10    
  SHARED DISPOSITIVE POWER 0
     
     
11  
  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
  1,852,972
 
     
12  
  CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES
  o
 
     
13  
  PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
  4.08%
 
     
14  
  TYPE OF REPORTING PERSON
  CO
2


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SCHEDULE 13D

                     
CUSIP No.
 
859823106 
 
           
1   NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

Siemens Beteiligungen Inland GmbH
     
     
2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

  (a)   o 
  (b)   þ 
     
3    
  SEC USE ONLY
   
     
4    
  SOURCE OF FUNDS OO
 
     
5    
  CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) or 2(e)
  o
     
6  
  CITIZENSHIP OR PLACE OF ORGANIZATION Federal Republic of Germany
 
       
  7    
  SOLE VOTING POWER 1,852,972
NUMBER OF    
       
SHARES 8    
BENEFICIALLY SHARED VOTING POWER 0
OWNED BY    
       
EACH 9    
REPORTING SOLE DISPOSITIVE POWER 1,852,972
PERSON    
       
WITH 10    
  SHARED DISPOSITIVE POWER 0
     
     
11  
  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
  1,852,972
 
     
12  
  CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES
  o
 
     
13  
  PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
  4.08%
 
     
14  
  TYPE OF REPORTING PERSON
  CO
3


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SCHEDULE 13D

                     
CUSIP No.
 
859823106 
 
           
1   NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

Siemens Aktiengesellschaft
     
     
2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

  (a)   o 
  (b)   þ 
     
3    
  SEC USE ONLY
   
     
4    
  SOURCE OF FUNDS OO
 
     
5    
  CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) or 2(e)
  o
     
6  
  CITIZENSHIP OR PLACE OF ORGANIZATION Federal Republic of Germany
 
       
  7    
  SOLE VOTING POWER 1,852,972
NUMBER OF    
       
SHARES 8    
BENEFICIALLY SHARED VOTING POWER 0
OWNED BY    
       
EACH 9    
REPORTING SOLE DISPOSITIVE POWER 1,852,972
PERSON    
       
WITH 10    
  SHARED DISPOSITIVE POWER 0
     
     
11  
  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
  1,852,972
 
     
12  
  CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES
  o
 
     
13  
  PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
  4.08%
 
     
14  
  TYPE OF REPORTING PERSON
  CO
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Item 5.          Interest in Securities of the Issuer
SIGNATURE


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This Amendment No. 3 (the “Amendment No. 3”) amends and supplements Item 5 of the Statement of Beneficial Ownership on Schedule 13D originally filed with the Securities and Exchange Commission on June 12, 2006, as amended by Amendment No. 1 filed on May 21, 2008, as further amended by Amendment No. 2 filed on May 30, 2008 (together, the “Schedule 13D”) relating to the beneficial ownership by Siemens Venture Capital GmbH (“Siemens Venture Capital”), Siemens Beteiligungen Inland GmbH (“Siemens Beteiligungen”) and Siemens Aktiengesellschaft (“Siemens AG”) (each, individually, a “Reporting Person” and collectively the “Reporting Persons”) of common stock, par value $0.001 per share (the “Common Stock”) of Sequenom, Inc., a Delaware corporation with principal executive offices at 3595 John Hopkins Court, San Diego, California 92121 (the “Issuer”). Unless specifically amended in this Amendment No. 3, the disclosures set forth in the Schedule 13D shall remain unchanged.
Item 5.          Interest in Securities of the Issuer
(a)-(b) As of May 30, 2008, Siemens Venture Capital beneficially owns 1,852,972 shares of Common Stock, representing approximately 4.08% of shares of Common Stock outstanding as of April 14, 2008. Siemens Venture Capital has sole voting and dispositive power with respect to such shares. For purposes of this Statement, Siemens AG and Siemens Beteiligungen are also reported as having voting and dispositive power over such shares by virtue of their respective control over Siemens Venture Capital. Siemens Beteiligungen, as Siemens Venture Capital’s sole shareholder, and Siemens AG, as Siemens Beteiligungen’s sole shareholder, may be deemed to own all such shares.
To the best of the Reporting Persons’ knowledge, none of the persons set forth in Exhibit B to Amendment No. 1 filed on May 21, 2008 beneficially owns any shares of Common Stock.
(c) Except as set forth below, there were no purchases or sales by any of the Reporting Persons, or to the best of the Reporting Persons’ knowledge, any of the persons set forth in Exhibit B to Amendment No. 1 filed on May 21, 2008, since May 28, 2008:
                         
Reporting Person                    
who effected the   Date of   Number of           Type of
Transaction   Transaction   Shares   Price Per Share   Transaction
Siemens Venture
Capital GmbH
  May 29, 2008     1,900     $ 7.5875     Open Market Sale
Siemens Venture
Capital GmbH
  May 29, 2008     1,200     $ 7.585     Open Market Sale
Siemens Venture
Capital GmbH
  May 29, 2008     500     $ 7.62     Open Market Sale
Siemens Venture
Capital GmbH
  May 29, 2008     300     $ 7.72     Open Market Sale
Siemens Venture
Capital GmbH
  May 29, 2008     100     $ 7.73     Open Market Sale
Siemens Venture
Capital GmbH
  May 29, 2008     2,300     $ 7.61     Open Market Sale
Siemens Venture
Capital GmbH
  May 29, 2008     100     $ 7.68     Open Market Sale

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Reporting Person                    
who effected the   Date of   Number of           Type of
Transaction   Transaction   Shares   Price Per Share   Transaction
Siemens Venture
Capital GmbH
  May 29, 2008     100     $ 7.67     Open Market Sale
Siemens Venture
Capital GmbH
  May 29, 2008     90,100     $ 7.6     Open Market Sale
Siemens Venture
Capital GmbH
  May 29, 2008     10,700     $ 7.59     Open Market Sale
Siemens Venture
Capital GmbH
  May 29, 2008     1,900     $ 7.58     Open Market Sale
Siemens Venture
Capital GmbH
  May 29, 2008     700     $ 7.57     Open Market Sale
Siemens Venture
Capital GmbH
  May 29, 2008     500     $ 7.56     Open Market Sale
Siemens Venture
Capital GmbH
  May 29, 2008     899     $ 7.55     Open Market Sale
Siemens Venture
Capital GmbH
  May 29, 2008     601     $ 7.54     Open Market Sale
Siemens Venture
Capital GmbH
  May 30, 2008     100     $ 7.855     Open Market Sale
Siemens Venture
Capital GmbH
  May 30, 2008     100     $ 7.8575     Open Market Sale
Siemens Venture
Capital GmbH
  May 30, 2008     100     $ 7.785     Open Market Sale
Siemens Venture
Capital GmbH
  May 30, 2008     100     $ 7.795     Open Market Sale
Siemens Venture
Capital GmbH
  May 30, 2008     700     $ 7.68     Open Market Sale
Siemens Venture
Capital GmbH
  May 30, 2008     1,100     $ 7.67     Open Market Sale
Siemens Venture
Capital GmbH
  May 30, 2008     600     $ 7.7425     Open Market Sale
Siemens Venture
Capital GmbH
  May 30, 2008     1,600     $ 7.69     Open Market Sale
Siemens Venture
Capital GmbH
  May 30, 2008     519,448     $ 7.65     Open Market Sale
Siemens Venture
Capital GmbH
  May 30, 2008     400     $ 7.875     Open Market Sale
Siemens Venture
Capital GmbH
  May 30, 2008     8,100     $ 7.865     Open Market Sale
Siemens Venture
Capital GmbH
  May 30, 2008     400     $ 7.885     Open Market Sale
Siemens Venture
Capital GmbH
  May 30, 2008     100     $ 7.8675     Open Market Sale
Siemens Venture
Capital GmbH
  May 30, 2008     800     $ 7.8975     Open Market Sale
Siemens Venture
Capital GmbH
  May 30, 2008     200     $ 7.895     Open Market Sale

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Reporting Person                    
who effected the   Date of   Number of           Type of
Transaction   Transaction   Shares   Price Per Share   Transaction
Siemens Venture
Capital GmbH
  May 30, 2008     20,700     $ 7.88     Open Market Sale
Siemens Venture
Capital GmbH
  May 30, 2008     5,088     $ 7.89     Open Market Sale
Siemens Venture
Capital GmbH
  May 30, 2008     4,223     $ 7.91     Open Market Sale
Siemens Venture
Capital GmbH
  May 30, 2008     9,300     $ 7.9     Open Market Sale
Siemens Venture
Capital GmbH
  May 30, 2008     14,873     $ 7.87     Open Market Sale
Siemens Venture
Capital GmbH
  May 30, 2008     24,733     $ 7.86     Open Market Sale
Siemens Venture
Capital GmbH
  May 30, 2008     39,997     $ 7.85     Open Market Sale
Siemens Venture
Capital GmbH
  May 30, 2008     400     $ 7.845     Open Market Sale
Siemens Venture
Capital GmbH
  May 30, 2008     9,296     $ 7.81     Open Market Sale
Siemens Venture
Capital GmbH
  May 30, 2008     23,585     $ 7.8     Open Market Sale
Siemens Venture
Capital GmbH
  May 30, 2008     14,743     $ 7.84     Open Market Sale
Siemens Venture
Capital GmbH
  May 30, 2008     8,922     $ 7.83     Open Market Sale
Siemens Venture
Capital GmbH
  May 30, 2008     18,400     $ 7.82     Open Market Sale
Siemens Venture
Capital GmbH
  May 30, 2008     80,747     $ 7.75     Open Market Sale
Siemens Venture
Capital GmbH
  May 30, 2008     12,364     $ 7.74     Open Market Sale
Siemens Venture
Capital GmbH
  May 30, 2008     22,942     $ 7.73     Open Market Sale
Siemens Venture
Capital GmbH
  May 30, 2008     12,177     $ 7.72     Open Market Sale
Siemens Venture
Capital GmbH
  May 30, 2008     30,471     $ 7.7     Open Market Sale
Siemens Venture
Capital GmbH
  May 30, 2008     1,400     $ 7.71     Open Market Sale
Siemens Venture
Capital GmbH
  May 30, 2008     31,100     $ 7.76     Open Market Sale
Siemens Venture
Capital GmbH
  May 30, 2008     13,887     $ 7.77     Open Market Sale
Siemens Venture
Capital GmbH
  May 30, 2008     11,249     $ 7.79     Open Market Sale
Siemens Venture
Capital GmbH
  May 30, 2008     10,825     $ 7.78     Open Market Sale

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Reporting Person                    
who effected the   Date of   Number of           Type of
Transaction   Transaction   Shares   Price Per Share   Transaction
Siemens Venture
Capital GmbH
  May 30, 2008     200     $ 7.775     Open Market Sale
(d) Not applicable.
(e) The Reporting Persons ceased to be beneficial owners of more than five percent of the Issuer’s securities as of the close of business on May 30, 2008.

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SIGNATURE
     After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement with respect to Siemens Venture Capital GmbH is true, complete and correct.
Dated: June 3, 2008
         
  SIEMENS VENTURE CAPITAL GMBH
 
 
  By:   /s/ DR. RALF SCHNELL    
    Name:   Dr. Ralf Schnell   
    Title:   CEO   
 
     
  By:   /s/ THOMAS KOLBINGER    
    Name:   Thomas Kolbinger   
    Title:   CFO   

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     After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement with respect to Siemens Beteiligungen Inland GmbH is true, complete and correct.
Dated: June 3, 2008
         
  SIEMENS BETEILIGUNGEN INLAND GMBH
 
 
  By:   /s/ GEORG BERNWIESER    
    Name:   Georg Bernwieser   
    Title:   Vice President   
 
     
  By:   /s/ WOLFGANG SELTMANN    
    Name:   Wolfgang Seltmann   
    Title:   Vice President   

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     After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement with respect to Siemens AG is true, complete and correct.
Dated: June 3, 2008
         
  SIEMENS AKTIENGESELLSCHAFT
 
 
  By:   /s/ DOMINIK ASAM    
    Name:   Dominik Asam   
    Title:   Managing Director and CEO
Siemens Financial Services GmbH  
 
         
     
  By:   /s/ SOLMS U. WITTIG    
    Name:   Solms U. Wittig   
    Title:   General Counsel Corporate and SFS   

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