SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549
                                   ----------

                                    FORM 8-A

                FOR REGISTRATION OF CERTAIN CLASSES OF SECURITIES
                    PURSUANT TO SECTION 12(b) OR 12(g) OF THE
                         SECURITIES EXCHANGE ACT OF 1934

                                 ISOLAGEN, INC.
             (Exact name of registrant as specified in its charter)


                        Delaware                             87-0458888
        (State of Incorporation or organization)          (I.R.S. Employer
                                                        Identification No.)

      405 Eagleview Boulevard, Exton, Pennsylvania           19341
        (Address of Principal Executive Offices)           (Zip Code)

If this form relates to the             If this form relates to the
registration of a class of securities   registration of a class of securities
pursuant to Section 12(b) of            pursuant to Section 12(g) of
the Exchange Act and is  effective      the Exchange Act and is effective
pursuant to General Instruction         pursuant to General Instruction
A.(c), please check the following       A.(d), please check the following
box. (  X  )                            box. (     )

Securities Act registration statement file number to which this form relates:
                                      N/A
                                 (If applicable)

Securities to be registered pursuant to Section 12(b) of the Act:

   Title of Each Class                      Name of Each Exchange on Which
   to be so Registered                      Each Class is to be Registered
   -------------------                      ------------------------------

 Rights to Purchase Series C Junior         American Stock Exchange
 Participating Preferred Stock
 (pursuant to Rights Agreement dated
 as of May 12, 2006)

Securities to be registered pursuant to Section 12(g) of the Act:
                                      None
 ------------------------------------------------------------------------------
                                (Title of Class)









Item 1.     Description of Registrant's Securities to be Registered.

     On May 12, 2006, the Board of Directors of Isolagen,  Inc. (the  "Company")
declared  a dividend  distribution  of one Right for each  outstanding  share of
common stock, par value $.001 per share, of the Company ("Company Common Stock")
to  stockholders of record at the close of business on May 22, 2006 (the "Record
Date"). Each Right entitles the registered holder to purchase from the Company a
unit consisting of one  ten-thousandth  of a share (a "Unit") of Series C Junior
Participating  Preferred Stock, par value $0.001 per share ("Preferred  Stock"),
at a Purchase Price of $35.00 per Unit,  subject to adjustment.  The description
and  terms  of the  Rights  are set  forth in a Rights  Agreement  (the  "Rights
Agreement")  between the Company and American Stock Transfer & Trust Company, as
Rights Agent.

     Initially,  the  Rights  will  be  attached  to all  Company  Common  Stock
certificates  representing  shares  then  outstanding,  and no  separate  Rights
Certificates will be distributed. Subject to certain exceptions specified in the
Rights  Agreement,  the Rights will separate from the Company Common Stock and a
Distribution  Date will occur upon the earlier of (i) 10 business days following
a public announcement that a person or group of affiliated or associated persons
(an "Acquiring Person") has acquired beneficial  ownership of 15% or more of the
outstanding  shares  of  Company  Common  Stock  (20%,  in the  case of  certain
institutional  investors)  other than as a result of repurchases of stock by the
Company  or  certain  inadvertent  actions by  institutional  or  certain  other
stockholders  (the "Stock  Acquisition  Date") or (ii) 10 business days (or such
later date as the Board shall determine)  following the commencement of a tender
offer or  exchange  offer that  would  result in a person or group  becoming  an
Acquiring Person.  Until the Distribution Date, (i) the Rights will be evidenced
by the Company Common Stock  certificates  and will be transferred with and only
with such  Company  Common  Stock  certificates,  (ii) new Company  Common Stock
certificates issued after the Record Date will contain a notation  incorporating
the Rights  Agreement by reference  and (iii) the  surrender for transfer of any
certificates  for Company  Common Stock  outstanding  will also  constitute  the
transfer of the Rights  associated with the Company Common Stock  represented by
such  certificate.  Pursuant to the Rights  Agreement,  the Company reserves the
right to require  prior to the  occurrence  of a  Triggering  Event (as  defined
below)  that,  upon any  exercise of Rights,  a number of Rights be exercised so
that only whole shares of Preferred Stock will be issued.

     The Rights are not exercisable  until the Distribution Date and will expire
at 5:00 P.M. (New York City time) on May 12, 2016,  unless such date is extended
or the Rights are earlier  redeemed  or  exchanged  by the Company as  described
below.





     As soon as practicable  after the Distribution  Date,  Rights  Certificates
will be mailed to holders of record of the Company  Common Stock as of the close
of  business on the  Distribution  Date and,  thereafter,  the  separate  Rights
Certificates alone will represent the Rights.  Except as otherwise determined by
the Board of Directors,  only shares of Company Common Stock issued prior to the
Distribution Date will be issued with Rights.

     In the event that a Person  becomes an Acquiring  Person,  each holder of a
Right will thereafter have the right to receive,  upon exercise,  Company Common
Stock (or, in certain  circumstances,  cash, property or other securities of the
Company)  having a value  equal to two times the  exercise  price of the  Right.
Notwithstanding any of the foregoing,  following the occurrence of the event set
forth in this  paragraph,  all Rights that are, or (under certain  circumstances
specified in the Rights  Agreement)  were,  beneficially  owned by any Acquiring
Person will be null and void. However,  Rights are not exercisable following the
occurrence  of the event set forth  above  until  such time as the Rights are no
longer redeemable by the Company as set forth below.

     For example, at an exercise price of $35.00 per Right, each Right not owned
by an Acquiring  Person (or by certain related  parties)  following an event set
forth in the preceding  paragraph  would  entitle its holder to purchase  $70.00
worth of  Company  Common  Stock (or other  consideration,  as noted  above) for
$35.00.  Assuming that the Company  Common Stock had a per share value of $10.00
at such time,  the holder of each valid  Right  would be  entitled to purchase 7
shares of Company Common Stock for $35.00.

     In the event that, at any time  following the Stock  Acquisition  Date, (i)
the Company  engages in a merger or other  business  combination  transaction in
which the Company is not the surviving corporation,  (ii) the Company engages in
a merger or other business  combination  transaction in which the Company is the
surviving  corporation and the Company Common Stock is changed or exchanged,  or
(iii) 50% or more of the Company's assets, cash flow or earning power is sold or
transferred,  each holder of a Right (except Rights which have  previously  been
voided as set forth  above)  shall  thereafter  have the right to receive,  upon
exercise,  common  stock of the  acquiring  company  having a value equal to two
times the exercise  price of the Right.  The events set forth in this  paragraph
and in  the  second  preceding  paragraph  are  referred  to as the  "Triggering
Events."

     At any time  after a person  becomes an  Acquiring  Person and prior to the
acquisition  by such  person  or  group of  fifty  percent  (50%) or more of the
outstanding  Company Common Stock, the Board may exchange the Rights (other than
Rights  owned by such person or group which have  become  void),  in whole or in
part,  at an  exchange  ratio  of one  share of  Company  Common  Stock,  or one
ten-thousandth of a share of Preferred Stock (or of a share of a class or series
of the Company's  preferred  stock having  equivalent  rights,  preferences  and
privileges), per Right (subject to adjustment).




     The Purchase Price payable,  and the number of Units of Preferred  Stock or
other securities or property  issuable,  upon exercise of the Rights are subject
to adjustment from time to time to prevent  dilution (i) in the event of a stock
dividend on, or a subdivision, combination or reclassification of, the Preferred
Stock,  (ii) if holders of the  Preferred  Stock are granted  certain  rights or
warrants to subscribe for Preferred Stock or convertible securities at less than
the current market price of the Preferred  Stock, or (iii) upon the distribution
to  holders  of the  Preferred  Stock of  evidences  of  indebtedness  or assets
(excluding  regular  quarterly  cash  dividends)  or of  subscription  rights or
warrants (other than those referred to above).

     With  certain  exceptions,  no  adjustment  in the  Purchase  Price will be
required  until  cumulative  adjustments  amount to at least 1% of the  Purchase
Price. No fractional Units will be issued and, in lieu thereof, an adjustment in
cash will be made based on the market price of the  Preferred  Stock on the last
trading date prior to the date of exercise.

     At any time until ten business days following the Stock  Acquisition  Date,
the  Company  may  redeem the  Rights in whole,  but not in part,  at a price of
$0.001 per Right (payable in cash,  Company Common Stock or other  consideration
deemed  appropriate by the Board of Directors).  The aggregate  redemption price
otherwise  payable  to a  beneficial  holder of Rights  shall be  rounded to the
nearest $0.01,  provided,  however,  if such aggregate  redemption price is less
than $0.01, such holder will be entitled to receive $0.01 upon the redemption of
such  Rights.  Immediately  upon the action of the Board of  Directors  ordering
redemption  of the Rights,  the Rights will  terminate and the only right of the
holders of Rights will be to receive the redemption price.

     Until a Right is  exercised,  the  holder  thereof,  as such,  will have no
rights as a stockholder of the Company, including, without limitation, the right
to vote or to receive  dividends.  While the distribution of the Rights will not
be taxable to stockholders or to the Company,  stockholders may,  depending upon
the circumstances,  recognize taxable income in the event that the Rights become
exercisable  for Company  Common  Stock (or other  consideration)  or for common
stock of the acquiring  company or in the event of the  redemption of the Rights
as set forth above.

     Any of the  provisions of the Rights  Agreement may be amended by the Board
of  Directors  of  the  Company  prior  to  the  Distribution  Date.  After  the
Distribution  Date, the provisions of the Rights Agreement may be amended by the
Board in order to cure any  ambiguity,  to make changes  which do not  adversely
affect the  interests  of holders of Rights,  or to shorten or lengthen any time
period under the Rights Agreement. The foregoing  notwithstanding,  no amendment
may be  made  to the  Rights  Agreement  at a  time  when  the  Rights  are  not
redeemable,  except to cure any ambiguity or correct or supplement any provision
contained in the Rights  Agreement which may be defective or  inconsistent  with
any other provision therein.




     The holder of each share of Company  Common Stock  outstanding at the close
of business on May 22,  2006 will  receive one Right.  So long as the Rights are
attached to the Company Common Stock,  one additional  Right (as such number may
be adjusted  pursuant to the provisions of the Rights Agreement) shall be deemed
to be delivered for each share of Company  Common Stock issued or transferred by
the Company in the future.  In addition,  following  the  Distribution  Date and
prior to the  expiration  or  redemption  of the  Rights,  the Company may issue
Rights  when it issues  Company  Common  Stock only if the Board  deems it to be
necessary  or  appropriate,  or in  connection  with the  issuance  of shares of
Company Common Stock pursuant to the exercise of stock options or under employee
plans or upon the exercise,  conversion or exchange of certain securities of the
Company.  10,000 shares of Preferred  Stock are initially  reserved for issuance
upon exercise of the Rights.

     The Rights may have  certain  anti-takeover  effects.  The Rights may cause
substantial  dilution to a person or group that  attempts to acquire the Company
in a manner which causes the Rights to become exercisable.  The Rights, however,
should not affect any  prospective  offeror  willing to make an offer at a price
that  is  fair  and  otherwise  in the  best  interest  of the  Company  and its
stockholders.  The Rights should not interfere with any merger or other business
combination  approved by the Board  since the Board may,  at its option,  at any
time until ten business  days  following the Stock  Acquisition  Date redeem the
then  outstanding  Rights at the Redemption Price or take other action to exempt
such a transaction under the Rights Agreement.

     The Rights  Agreement,  dated as of May 12,  2006,  between the Company and
American Stock Transfer & Trust Company,  as Rights Agent,  specifying the terms
of the Rights is  attached  hereto as an exhibit and is  incorporated  herein by
reference.  The foregoing description of the Rights is qualified in its entirety
by reference to such exhibit.

Item 2.     Exhibits.

            1.       Rights Agreement, dated as of May 12, 2006, by and
                     between the registrant and American Stock Transfer &
                     Trust Company, including the Form of Certificate of
                     Designation, Preferences and Rights of Series C
                     Junior Participating Preferred Stock attached as
                     Exhibit A thereto, the Form of Rights Certificate
                     attached as Exhibit B thereto and the Summary of
                     Rights to Purchase Preferred Stock attached as
                     Exhibit C thereto (incorporated by reference to
                     Exhibit 4.1 to the Current Report on Form 8-K filed
                     by the registrant with the Securities and Exchange
                     Commission on May 15, 2006).







                                    SIGNATURE

     Pursuant to the  requirements of Section 12 of the Securities  Exchange Act
of 1934, the Registrant has duly caused this registration statement to be signed
on its behalf by the undersigned, thereunto duly authorized.


                                   ISOLAGEN, INC.
                                   (Registrant)


Date: May 15, 2006                 By: /s/ Todd Greenspan
                                       ----------------------------------------
                                       Name: Todd Greenspan
                                       Title: Vice President of Finance




                                  EXHIBIT INDEX

      Exhibit            Description
      -------            -----------

         1.              Rights Agreement, dated as of May 12, 2006, by and
                         between the registrant and American Stock Transfer &
                         Trust Company, including the Form of Certificate of
                         Designation, Preferences and Rights of Series C Junior
                         Participating Preferred Stock attached as Exhibit A
                         thereto, the Form of Rights Certificate attached as
                         Exhibit B thereto and the Summary of Rights to Purchase
                         Preferred Stock attached as Exhibit C thereto
                         (incorporated by reference to Exhibit 4.1 to the
                         Current Report on Form 8-K filed by the registrant with
                         the Securities and Exchange Commission on May 15,
                         2006).