As filed with the Securities and Exchange Commission on October 17, 2003
                                                    Registration No. 333-_______

                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                    FORM S-8

                             REGISTRATION STATEMENT
                                      UNDER
                           THE SECURITIES ACT OF 1933

                                 WESBANCO, INC.
             (Exact name of registrant as specified in its charter)

          West Virginia                                          55-0571723
    (State or other jurisdiction                               (I.R.S. Employer
 of incorporation or organization)                           Identification No.)

            One Bank Plaza                                           26003
       Wheeling, West Virginia                                     (Zip Code)
(Address of Principal Executive Offices)


                               WESBANCO, INC. KSOP
                            (Full title of the plan)

                                 Paul M. Limbert
                      President and Chief Executive Officer
                                 One Bank Plaza
                               Wheeling, WV 26003
                     (Name and address of agent for service)

                                 (304) 234-9000
          (Telephone number, including area code, of agent for service)



                                 With Copies To:

James C. Gardill, Esquire                            J. Robert Van Kirk, Esquire
Phillips, Gardill, Kaiser & Altmeyer, PLLC           Kirkpatrick & Lockhart LLP
61 Fourteenth Street                                 Henry W. Oliver Building
Wheeling, WV  26003                                  535 Smithfield Street
(304) 232-6810                                       Pittsburgh, PA 15222
                                                     (412) 355-6500






                                                                        


                         CALCULATION OF REGISTRATION FEE
--------------------------------------------------------------------------------------------------------------
                                                 Proposed            Proposed
         Title of                                 maximum             maximum       Amount of registration fee
        securities              Amount to be    offering price       aggregate
    to be registered(1)       registered (2)     per share (3)     offering price(3)
---------------------------------------------------------------------------------------------------------------
Common Stock, $2.0833 par        200,000           $24.43            $4,886,000               $395.30
value per share
---------------------------------------------------------------------------------------------------------------




(1) Pursuant to Rule 416(c) under the  Securities  Act of 1933,  as amended (the
"Securities Act"), this Registration Statement covers an indeterminate number of
interests  to be  offered  or sold  pursuant  to the  WesBanco,  Inc.  KSOP (the
"Plan").

(2)  Pursuant  to Rule  416(a)  under  the  Securities  Act,  this  Registration
Statement  also covers an  indeterminate  number of additional  shares of Common
Stock as may be offered or issued under the Plan to prevent  dilution  resulting
from stock splits, stock dividends or similar transactions.

(3)  Estimated  solely  for the  purpose of  calculating  the  registration  fee
pursuant to Rule 457(h)(1) and Rule 457(c) under the Securities  Act. The fee is
calculated  on the  basis of the  average  of the high  and low  prices  for the
Registrant's  Common  Stock,  $2.0833  par  value per  share  ("Common  Stock"),
reported on the NASDAQ Stock Market on October 13, 2003.







                                EXPLANATORY NOTE

     This  Registration  Statement  is being  filed to  register  an  additional
200,000  shares of Common Stock under the WesBanco,  Inc. KSOP as a result of an
increase  in  the  number  of  shares  issuable  under  the  Plan.  The  earlier
Registration  Statement on Form S-8 filed by the Registrant  with the Securities
and  Exchange   Commission  (the  "Commission")  on  June  25,  1996  (File  No.
333-06741), is hereby incorporated by reference. This incorporation by reference
is made pursuant to General Instruction E of Form S-8 regarding the registration
of additional  securities of the same class as other  securities for which there
is a  Registration  Statement on Form S-8 relating to the same employee  benefit
plan.







                                      II-1








                                     PART II
               INFORMATION REQUIRED IN THE REGISTRATION STATEMENT


      Item 3.     Incorporation of Documents by Reference.

     The following  documents  filed by the  Registrant  with the Securities and
Exchange  Commission (the "Commission")  pursuant to the Securities Exchange Act
of 1934, as amended (the"Exchange Act"), are incorporated by reference into this
Registration Statement:  (i) the Registrant's Annual Report on Form 10-K for the
fiscal year ended December 31, 2002 (File No. 000-08467);  (ii) the Registrant's
Quarterly  Reports on Form 10-Q for the  quarters  ended March 31, 2003 and June
30, 2003; (iii) the Registrant's  Current Reports on Form 8-K filed on April 18,
2003,  April 22, 2003,  July 1, 2003,  July 18, 2003 and September 2, 2003;  and
(iv)  the  description  of  the  Registrant's  Common  Stock  contained  in  the
Registrant's Registration Statement on Form 8-A filed on May 2, 1977, as amended
on June 10, 1977.

     All documents  subsequently  filed by the  Registrant  with the  Commission
pursuant to Sections  13(a),  13(c),  14 and 15(d) of the Exchange Act after the
date of this Registration Statement, but prior to the filing of a post-effective
amendment to this  Registration  Statement  which  indicates that all securities
offered by this  Registration  Statement have been sold or which deregisters all
such  securities  then remaining  unsold,  shall be deemed to be incorporated by
reference  into this  Registration  Statement.  Each  document  incorporated  by
reference into this Registration  Statement shall be deemed to be a part of this
Registration  Statement  from  the  date of  filing  of such  document  with the
Commission until the information  contained  therein is superseded or updated by
any  subsequently  filed document which is  incorporated  by reference into this
Registration  Statement  or by  any  document  which  constitutes  part  of  the
prospectus  relating to the  WesBanco,  Inc.  KSOP meeting the  requirements  of
Section 10(a) of the Securities Act of 1933, as amended.


      Item 8.     Exhibits.

     The following  exhibits are filed herewith or  incorporated by reference as
part of this Registration Statement:


  Exhibit No.                        Description

   5.1         Opinion  of James C.  Gardill,  Esquire,  of  Phillips,  Gardill,
               Kaiser & Altmeyer,  PLLC,  regarding  the  legality of the shares
               being registered hereunder (filed herewith).


   23.1        Consent of Ernst & Young LLP (filed herewith).

   23.2        Consent of James C. Gardill, Esquire of Phillips, Gardill, Kaiser
               & Altmeyer, PLLC (included in the Opinion filed as Exhibit 5.1).

   24.1        Power  of  Attorney  (set  forth  on the  signature  page of this
               Registration Statement).






                                      II-2



                                   SIGNATURES

     Pursuant  to  the  requirements  of  the  Securities  Act,  the  registrant
certifies  that it has  reasonable  grounds to believe  that it meets all of the
requirements  for  filing  on Form S-8 and has  duly  caused  this  Registration
Statement  to be  signed  on its  behalf  by  the  undersigned,  thereunto  duly
authorized, in the City of Wheeling, State of West Virginia, on this 16th day of
October, 2003.

                                       WESBANCO, INC.

                                       By: /s/  Paul M. Limbert
                                           -------------------------------------
                                           Paul M. Limbert
                                           President and Chief Executive Officer

     KNOW ALL MEN BY THESE PRESENTS,  that each person whose  signature  appears
below  constitutes  and  appoints  Robert H.  Young  his or her true and  lawful
attorney-in-fact  and agent, with full power of substitution and resubstitution,
for  him  or her  and in his or her  name,  place  and  stead,  in any  and  all
capacities,  to sign any and all amendments to this Registration Statement,  and
to file  the  same,  with all  exhibits  thereto,  and  other  documentation  in
connection therewith, with the Securities and Exchange Commission, granting unto
said  attorney-in-fact and agent with full power and authority to do and perform
each and every act and thing  requisite and necessary to be done in or about the
premises, as fully to all intents and purposes as he or she might or could do in
person,  hereby  ratifying and  confirming all that said  attorneys-in-fact  and
agents,  or their  substitute or substitutes may lawfully do or cause to be done
by virtue hereof.

     Pursuant to the  requirements  of the  Securities  Act,  this  registration
statement has been signed by the following  persons in the capacities and on the
date(s) indicated:



                                                                                             

             Signature                                  Capacity                                       Date
             ---------                                  --------                                       ----

 /s/ James E. Altmeyer                         Director                                         October 16, 2003
 --------------------------------------------
 James E. Altmeyer

 /s/ Ray A. Byrd                               Director                                         October 16, 2003
 --------------------------------------------
 Ray A. Byrd

 /s/ R. Peterson Chalfant                      Director                                         October 16, 2003
 --------------------------------------------
 R. Peterson Chalfant

 /s/ John H. Cheffy                            Director                                         October 16, 2003
 --------------------------------------------
 John H. Cheffy

 /s/ Christopher V. Criss                      Director                                         October 16, 2003
 --------------------------------------------
 Christopher V. Criss



                                      II-3





             Signature                                  Capacity                                       Date
             ---------                                  --------                                       ----

 /s/ James D. Entress                          Director                                         October 16, 2003
 --------------------------------------------
 James D. Entress

 /s/ Abigail N. Feinknopf                      Director                                         October 16, 2003
 --------------------------------------------
 Abigail M. Feinknopf

 /s/ Ernest S. Fragale                         Director                                         October 16, 2003
 --------------------------------------------
 Ernest S. Fragale

 /s/ Edward M. George                          Chairman, Director                               October 16, 2003
 --------------------------------------------
 Edward M. George

 /s/ Roland L. Hobbs                           Director                                         October 16, 2003
 --------------------------------------------
 Roland L. Hobbs

 /s/ John W. Kepner                            Director                                         October 16, 2003
 --------------------------------------------
 John W. Kepner

 /s/ Paul M. Limbert                           President and Chief Executive Officer            October 16, 2003
 --------------------------------------------  (Principal Executive Officer)
 Paul M. Limbert

 /s/ Jay T. McCamic                            Director                                         October 16, 2003
 --------------------------------------------
 Jay T. McCamic

 /s/ William E. Mildren, Jr.                   Director                                         October 16, 2003
 --------------------------------------------
 William E. Mildren, Jr.

                                               Director
 --------------------------------------------
 Joan C. Stamp

                                               Director
 --------------------------------------------
 Carter W. Strauss

 /s/ Reed J. Tanner                            Director                                         October 16, 2003
 --------------------------------------------
 Reed J. Tanner

 /s/ Robert K. Tebay                           Director                                         October 16, 2003
 --------------------------------------------
 Robert K. Tebay

 /s/ Robert H. Young                           Executive Vice President and Chief               October 16, 2003
 --------------------------------------------  Financial Officer (Principal Financial and
 Robert H. Young                               Accounting Officer)




                                      II-4






                                                   EXHIBIT INDEX

 Exhibit No.                                 Description

   5.1              Opinion of James C. Gardill, Esquire, of Phillips,  Gardill,
                    Kaiser &  Altmeyer,  PLLC,  regarding  the  legality  of the
                    shares being registered hereunder (filed herewith).

   23.1             Consent of Ernst & Young LLP (filed herewith).

   23.2             Consent of James C. Gardill,  Esquire of Phillips,  Gardill,
                    Kaiser & Altmeyer,  PLLC  (included in the Opinion  filed as
                    Exhibit 5.1).

   24.1             Power of Attorney (set forth on the  signature  page of this
                    Registration Statement).





                                      II-5