UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549


                                  SCHEDULE 13G

                   Under the Securities Exchange Act of 1934*


                             GEN-PROBE INCORPORATED
 ------------------------------------------------------------------------------
                                (Name of Issuer)

                    Common Stock, $0.0001 Par Value Per Share
 ------------------------------------------------------------------------------
                         (Title of Class of Securities)

                                    36866T103
                                    ---------
                                 (CUSIP Number)


                               September 20, 2001
                               ------------------
                      (Date of Event which Requires Filing
                               of this Statement)



Check the appropriate box to designate the rule pursuant to which this Schedule
is filed:

            [ ]   Rule 13d-1(b)
            [X]   Rule 13d-1(c)
            [ ]   Rule 13d-1(d)



*The remainder of this cover page shall be filled out for a reporting person's
 initial filing on this form with respect to the subject class of securities,
 and for any subsequent amendment containing information which would alter the
 disclosures provided in a prior cover page.

 The information required on the remainder of this cover page shall not be
 deemed to be "filed" for the purpose of Section 18 of the Securities Exchange
 Act of 1934 ("Act") or otherwise subject to the liabilities of that section of
 the Act but shall be subject to all other provisions of the Act (however, see
 the Notes).



                               Page 1 of 8 pages



----------------------                              ---------------------------
CUSIP No.  36866T103                  13G                 Page 2 of 8 Pages
----------------------                              ---------------------------

-------- ----------------------------------------------------------------------
    1    NAME OF REPORTING PERSON
         I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS

         S.A.C. Capital Advisors, LLC
-------- ----------------------------------------------------------------------
    2    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*      (a)  [ ]
                                                                (b)  [X]

-------- ----------------------------------------------------------------------
    3    SEC USE ONLY


-------- ----------------------------------------------------------------------
    4    CITIZENSHIP OR PLACE OF ORGANIZATION

         Delaware
-------------------------------------------------------------------------------
                 5      SOLE VOTING POWER

 NUMBER OF              0
  SHARES      --------- -------------------------------------------------------
BENEFICIALLY     6      SHARED VOTING POWER
   OWNED
    BY                  2,285,000
   EACH       --------- -------------------------------------------------------
 REPORTING       7      SOLE DISPOSITIVE POWER
  PERSON
   WITH                 0
              --------- -------------------------------------------------------
                 8      SHARED DISPOSITIVE POWER

                        2,285,000
-------------------------------------------------------------------------------
    9    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

         2,285,000
-------- ----------------------------------------------------------------------
   10    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES

         [ ]
-------- ----------------------------------------------------------------------
   11    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

         9.6%
-------- ----------------------------------------------------------------------
   12    TYPE OF REPORTING PERSON*

         00
-------- ----------------------------------------------------------------------

                      *SEE INSTRUCTION BEFORE FILLING OUT





----------------------                              ---------------------------
CUSIP No.  36866T103                  13G                 Page 3 of 8 Pages
----------------------                              ---------------------------

-------- ----------------------------------------------------------------------
    1    NAME OF REPORTING PERSON
         I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS

         S.A.C. Capital Management, LLC
-------- ----------------------------------------------------------------------
    2    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*      (a)  [ ]
                                                                (b)  [X]

-------- ----------------------------------------------------------------------
    3    SEC USE ONLY


-------- ----------------------------------------------------------------------
    4    CITIZENSHIP OR PLACE OF ORGANIZATION

         Delaware
-------------------------------------------------------------------------------
                 5      SOLE VOTING POWER

 NUMBER OF              0
  SHARES      --------- -------------------------------------------------------
BENEFICIALLY     6      SHARED VOTING POWER
   OWNED
    BY                  2,285,000
   EACH       --------- -------------------------------------------------------
 REPORTING       7      SOLE DISPOSITIVE POWER
  PERSON
   WITH                 0
              --------- -------------------------------------------------------
                 8      SHARED DISPOSITIVE POWER

                        2,285,000
-------------------------------------------------------------------------------
    9    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

         2,285,000
-------- ----------------------------------------------------------------------
   10    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES

         [ ]
-------- ----------------------------------------------------------------------
   11    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

         9.6%
-------- ----------------------------------------------------------------------
   12    TYPE OF REPORTING PERSON*

         00
-------- ----------------------------------------------------------------------

                      *SEE INSTRUCTION BEFORE FILLING OUT





----------------------                              ---------------------------
CUSIP No.  36866T103                  13G                 Page 4 of 8 Pages
----------------------                              ---------------------------

-------- ----------------------------------------------------------------------
    1    NAME OF REPORTING PERSON
         I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS

         Steven A. Cohen
-------- ----------------------------------------------------------------------
    2    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*      (a)  [ ]
                                                                (b)  [X]

-------- ----------------------------------------------------------------------
    3    SEC USE ONLY


-------- ----------------------------------------------------------------------
    4    CITIZENSHIP OR PLACE OF ORGANIZATION

         United States
-------------------------------------------------------------------------------
                 5      SOLE VOTING POWER

 NUMBER OF              0
  SHARES      --------- -------------------------------------------------------
BENEFICIALLY     6      SHARED VOTING POWER
   OWNED
    BY                  2,285,000
   EACH       --------- -------------------------------------------------------
 REPORTING       7      SOLE DISPOSITIVE POWER
  PERSON
   WITH                 0
              --------- -------------------------------------------------------
                 8      SHARED DISPOSITIVE POWER

                        2,285,000
-------------------------------------------------------------------------------
    9    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

         2,285,000
-------- ----------------------------------------------------------------------
   10    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES

         [ ]
-------- ----------------------------------------------------------------------
   11    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

         9.6%
-------- ----------------------------------------------------------------------
   12    TYPE OF REPORTING PERSON*

         IN
-------- ----------------------------------------------------------------------

                      *SEE INSTRUCTION BEFORE FILLING OUT





Item 1(a)               Name of Issuer:
                        --------------

                        Gen-Probe Incorporated

Item 1(b)               Address of Issuer's Principal Executive Offices:
                        -----------------------------------------------

                        10210 Genetic Center Drive
                        San Diego, CA 92121

Items 2(a)              Name of Person Filing:
                        ---------------------

                        This statement is being filed by (i) S.A.C. Capital
                        Advisors, LLC ("SAC Capital Advisors"), (ii) S.A.C.
                        Capital Management, LLC ("SAC Capital Management")
                        and (iii) Steven A. Cohen.

Item 2(b)               Address of Principal Business Office:
                        ------------------------------------

                        (i), (ii) and (iii):
                        777 Long Ridge Road
                        Stamford, Connecticut 06902

Item 2(c)               Citizenship:
                        -----------

                        (i):  Delaware
                        (ii): Delaware
                        (iv): United States

Item 2(d)               Title of Class of Securities:
                        ----------------------------

                        Common Stock, par value $0.0001 per share

Item 2(e)               CUSIP Number:
                        ------------

                        36866T103

Item 3                  Not Applicable

Item 4                  Ownership:
                        ---------

Of the securities reported on herein, 1,785,000 shares are held by S.A.C.
Capital Associates, LLC, an Anguillan limited liability company ("SAC Capital
Associates") and 500,000 shares are held by S.A.C. Healthco Fund, LLC, an
Anguillan limited liability company ("SAC Healthco"). Pursuant to investment
agreements, each of SAC Capital Advisors and SAC Capital Management share all
investment and voting power with respect to the securities held by SAC Capital
Associates and SAC Healthco. Accordingly, each of SAC Capital Advisors and SAC
Capital Management may be deemed to be the beneficial owner of the securities
held by SAC Capital Associates and SAC



                               Page 5 of 8 pages



Healthco reported herein for purposes of Rule 13d-3 under the Securities
Exchange Act of 1934 (the "Exchange Act").

Steven A. Cohen is (i) the President and Chief Executive Officer of SAC Capital
Advisors, the Managing Member of which is a corporation wholly owned by Mr.
Cohen and (ii) the owner, directly and through a wholly owned subsidiary, of
100% of the membership interests of SAC Capital Management. Accordingly, Mr.
Cohen may be deemed to be the beneficial owner of the securities covered by this
statement for purposes of Rule 13d-3 under the Exchange Act. Mr. Cohen disclaims
beneficial ownership of any of the securities covered by this statement.

Item 4(a)               Amount Beneficially Owned:
                        -------------------------

                        2,285,000

Item 4(b)               Percent of Class:
                        ----------------

                        9.6%

Item 4(c)               Number of shares as to which such person has:
                        --------------------------------------------

                        (i)   Sole power to vote or to direct the vote:  0

                        (ii)  Shared power to vote or to direct the vote:
                              2,285,000

                        (iii) Sole power to dispose or to direct the
                              disposition of:  0

                        (iv)  Shared power to dispose or to direct the
                              disposition of:  2,285,000

Item 5                  Ownership of Five Percent or Less of a Class:
                        --------------------------------------------

                        If this statement is being filed to report the fact that
                        as of the date hereof the reporting person has ceased to
                        be the beneficial owner of more than five percent of the
                        class of securities, check the following.



                               Page 6 of 8 pages



Item 6                  Ownership of More than Five Percent on Behalf of
                        ------------------------------------------------
                        Another Person:
                        --------------

                        SAC Capital Associates and SAC Healthco have the right
                        to receive dividends on, and proceeds from the sale of,
                        the shares reported on this statement as beneficially
                        owned by SAC Capital Advisors, SAC Capital Management,
                        and Mr. Cohen.

Item 7                  Identification and Classification of the
                        ----------------------------------------
                        Subsidiary Which Acquired the Security Being
                        --------------------------------------------
                        Reported on By the Parent Holding Company:
                        -----------------------------------------

                        Not Applicable

Item 8                  Identification and Classification of Members
                        ---------------------------------------------
                        of the Group:
                        ------------

                        Not Applicable


Item 9                  Notice of Dissolution of Group:
                        ------------------------------

                        Not Applicable

Item 10                 Certification:

      By signing below the signatory certifies that, to the best of his
knowledge and belief, the securities referred to above were not acquired and are
not held for the purpose of or with the effect of changing or influencing the
control of the issuer of the securities and were not acquired and are not held
in connection with or as a participant in any transaction having that purpose or
effect.



                               Page 7 of 8 pages



                                   SIGNATURE
                                   ---------

      After reasonable inquiry and to the best of my knowledge and belief, I
certify that the information set forth in this statement is true, complete and
correct.



Dated:  September 27, 2002


S.A.C. CAPITAL ADVISORS, LLC


By:/s/ Peter Nussbaum
   ------------------------------
   Name:   Peter Nussbaum
   Title:  Authorized Person



S.A.C. CAPITAL MANAGEMENT, LLC


By:/s/ Peter Nussbaum
   ------------------------------
   Name:   Peter Nussbaum
   Title:  Authorized Person



STEVEN A. COHEN


By:/s/ Peter Nussbaum
   ------------------------------
   Name:   Peter Nussbaum
   Title:  Authorized Person



                               Page 8 of 8 pages