PAGE 1 000 B000000 10/31/2011 000 C000000 0000925683 000 D000000 N 000 E000000 NF 000 F000000 Y 000 G000000 Y 000 H000000 N 000 I000000 6.1 000 J000000 A 001 A000000 JOHN HANCOCK BANK AND THRIFT OPPORTUNITY FUND 001 B000000 811-8568 001 C000000 6176634497 002 A000000 601 CONGRESS STREET 002 B000000 BOSTON 002 C000000 MA 002 D010000 02210 002 D020000 2805 003 000000 N 004 000000 N 005 000000 N 006 000000 N 007 A000000 N 007 B000000 0 007 C010100 1 077 A000000 Y 077 B000000 Y 077 C000000 N 077 D000000 N 077 E000000 N 077 F000000 N 077 G000000 N 077 H000000 N 077 I000000 N 077 J000000 N 077 K000000 N 077 L000000 N 077 M000000 N 077 N000000 N 077 O000000 N 077 P000000 N 077 Q010000 N 077 Q020000 N 077 Q030000 N SIGNATURE SALVATORE SCHIAVONE TITLE TREASURER This Form N-SAR B is updated for the inclusion of the Independent Registered Public Accountant's Name and location, as shown in Exhibit EX-99-77B ACCT LTR