Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number: 3235-0287
Expires: January 31, 2005
Estimated average burden hours per response... 0.5

(Print or Type Responses)
1. Name and Address of Reporting Person *
COZADD BRUCE C
  2. Issuer Name and Ticker or Trading Symbol
Jazz Pharmaceuticals plc [JAZZ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
__X__ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
Chairman and CEO
(Last)
(First)
(Middle)
C/O JAZZ PHARMACEUTICALS PLC, CONNAUGHT HOUSE, 1 BURLINGTON RD, FL. 4
3. Date of Earliest Transaction (Month/Day/Year)
03/21/2013
(Street)

DUBLIN 4, L2 
4. If Amendment, Date Original Filed(Month/Day/Year)
6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)
7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Ordinary Shares 03/21/2013   M   15,902 A $ 15.09 638,063 D  
Ordinary Shares 03/21/2013   M   5,299 A $ 30.18 643,362 D  
Ordinary Shares 03/21/2013   M   5,299 A $ 45.27 648,661 D  
Ordinary Shares 03/21/2013   M   12,583 A $ 19.37 661,244 D  
Ordinary Shares 03/21/2013   M   7,040 A $ 7.96 668,284 D  
Ordinary Shares 03/21/2013   M   182 A $ 1.25 668,466 D  
Ordinary Shares 03/21/2013   M   2,177 A $ 11.48 670,643 D  

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number. SEC 1474 (9-02)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)
6. Date Exercisable and Expiration Date
(Month/Day/Year)
7. Title and Amount of Underlying Securities
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)
11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Incentive Stock Option (right to buy) $ 15.09 03/21/2013   M     15,902   (1) 02/17/2014 Ordinary Shares 15,902 $ 0 0 D  
Incentive Stock Option (right to buy) $ 30.18 03/21/2013   M     5,299   (1) 02/17/2014 Ordinary Shares 5,299 $ 0 0 D  
Incentive Stock Option (right to buy) $ 45.27 03/21/2013   M     5,299   (1) 02/17/2014 Ordinary Shares 5,299 $ 0 0 D  
Incentive Stock Option (right to buy) $ 19.37 03/21/2013   M     12,583   (2) 02/26/2017 Ordinary Shares 12,583 $ 0 0 D  
Incentive Stock Option (right to buy) $ 7.96 03/21/2013   M     7,040   (3) 05/15/2018 Ordinary Shares 7,040 $ 0 0 D  
Incentive Stock Option (right to buy) $ 1.25 03/21/2013   M     182   (4) 01/20/2019 Ordinary Shares 182 $ 0 0 D  
Incentive Stock Option (right to buy) $ 11.48 03/21/2013   M     2,177   (5) 03/07/2020 Ordinary Shares 2,177 $ 0 15,243 D  

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
COZADD BRUCE C
C/O JAZZ PHARMACEUTICALS PLC
CONNAUGHT HOUSE, 1 BURLINGTON RD, FL. 4
DUBLIN 4, L2 
  X     Chairman and CEO  

Signatures

 /s/ Larissa Schwartz as attorney in fact for Bruce Cozadd   03/22/2013
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) This option fully vested on February 18, 2008.
(2) This option fully vested on February 27, 2012.
(3) This option fully vested on April 8, 2012.
(4) This option fully vested on January 21, 2012.
(5) Following the reported transaction, the remaining ordinary shares subject to this option vest with respect to 6,533 shares in nine equal monthly installments from April 8, 2013 to December 8, 2013 and with respect to 8,710 shares in three equal monthly installments from January 8, 2014 to March 8, 2014.

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.

Potential persons who are to respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB number.