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September 01, 2020 10:27am
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Mixed open as pending home sales falls

The markets opened mixed with the Dow rising 16 points to 18,356 while Nasdaq lost 12 points to 5,306 as pending home sales fell 2.4% in August.

On the upside

Catabasis Pharmaceuticals (Nasdaq: CATB) entered a joint research collaboration with Sarepta Therapeutics (Nasdaq: SRPT) to explore a combination drug treatment approach for Duchenne muscular dystrophy.

Japan's Ministry of Health, Labor & Welfare approved Aegerion Pharmaceuticals' (Nasdaq: AEGR) JUXTAPID to treat homozygous familial hypercholesterolemia.

Mimecast (Nasdaq: MIME) priced its secondary offering of 4 million common shares at the discounted price of $16.50 per share.

On the downside

The Food and Drug Administration's Division of Psychiatry Products placed a full clinical hold on Alcobra's (Nasdaq: ADHD) Investigational New Drug applications for MDX in Attention Deficit Hyperactivity Disorder and Fragile X Syndrome.

Pacific Crest downgraded Fitbit (NYSE: FIT) from a Sector Weight rating to an Underweight rating.

Intra-Cellular Therapies (Nasdaq: ITCI) reported disappointing results from a Phase 3 trial of ITI-007 to treat schizophrenia prompting a downgrade.

In the broad market, declining issues outpaced advancers by a margin of more than 7 to 5 on the NYSE and by 5 to 3 on Nasdaq. The broader S&P 500 held steady at 2,171. Bitcoin eased a fraction to $603.

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