New York, USA – June 1, 2022 – Cell Assay, the mature branch of Creative Bioarray, focuses on accelerating the research of cell apoptosis, cell necrosis, autophagy, ferroptosis, pyroptosis and other fields. Creative Bioarray is always committed to providing a full range of research consulting, design, implementation, management, reporting and analysis services. Recently, Creative Bioarray announced the release of its tube formation assay that can be applied for high throughput screening to identify factors that stimulate or inhabit angiogenesis.
Angiogenesis is critical for tumorigenesis and metastasis. The HUVECs tube formation assay is a simple but well-established in vitro angiogenesis assay based on the ability of ECs to form three-dimensional capillary-like tubular structures representing the later stages of the angiogenesis process. During the assay, HUVEC cells differentiate, migrate directionally to align, branch, and form a polygonal network of blood vessels.
Tube formation assays have been widely used to solve various experimental problems. The basement membrane surface and its components are critical for successful tube formation assays. Different types of basement membranes (eg, Matrigel®, collagen, or other hydrogel matrices) can be applied, which result in different rates of tube formation. Endothelial cells differentiate morphologically to form tubes. Cells first attach to the matrix and migrate to each other. They then attach to other cells, aligning and forming capillary-like tubes. Tubes mature until cells eventually undergo apoptosis, resulting in detachment from the surface and tube destruction.
Tube Formation Assay from Creative Bioarray is a widely used in vitro tool for accessing angiogenesis in a simple, cost-effective and reproducible manner. The use of only one cell type guarantees well-defined experimental parameters, which greatly facilitates analytical analysis.
“Our experienced research team can provide you with a variety of services on cell growth and cell death research. With advanced instruments and talented and well-trained experts, we work closely with partners from all over the world to provide targeted technical support.” said Hannah Cole, the marketing director of Creative Bioarray, she also added, “We provide one-stop service, from order to final report, to provide the best solution for your research, and our skilled team is capable to offer customized solutions for individual programs.”
About Creative Bioarray
Creative Bioarray is dedicated to offering customers with innovative biotechnology products and services for research use to greatly enhance and drive innovation and standards in science. As a well-recognized industry leader with more than 10 years of experience and in-house experts supported, Creative Bioarray has already countenanced research all around the world.