The San Francisco 49ers will usher in the Trey Lance era Week 1 against the Chicago Bears, and, with Deebo Samuel still in the picture, everything appears to be coming together for the team.
The 49ers boast a fearsome defense with Nick Bosa, Javon Kinlaw and Fred Warner among those holding down the fort.
The team came just short of a Super Bowl bid last year and will likely be back in that same mix this season. Week 4 and Week 8 both feature an NFC championship rematch between the Niners and Los Angeles Rams.
Read below for the 49ers' schedule, how to watch games and where to watch.
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Week 1: San Francisco 49ers @ Chicago Bears, September 11, 2022
TV: FOX
Time: 1 p.m. ET
Week 2: San Francisco 49ers vs. Seattle Seahawks, September 18, 2022
TV: FOX
Time: 4:05 p.m. ET
Week 3: San Francisco 49ers @ Denver Broncos, September 25, 2022
TV: NBC
Time: 8:20 p.m. ET
Week 4: San Francisco 49ers vs. Los Angeles Rams, October 3, 2022
TV: ESPN
Time: 8:15 p.m. ET
Week 5: San Francisco 49ers @ Carolina Panthers, October 9, 2022
TV: CBS
Time: 4:05 p.m. ET
Week 6: San Francisco 49ers @ Atlanta Falcons, October 16, 2022
TV: FOX
Time: 1 p.m. ET
Week 7: San Francisco 49ers vs. Kansas City Chiefs, October 23, 2022
TV: FOX
Time: 4:25 p.m. ET
Week 8: San Francisco 49ers @ Los Angeles Rams, October 30, 2022
TV: FOX
Time: 4:25 p.m. ET
Week 9: BYE
Week 10: San Francisco 49ers vs. Los Angeles Chargers, November 13, 2022
TV: NBC
Time: 8:20 p.m. ET
Week 11: San Francisco 49ers vs. Arizona Cardinals, November 21, 2022
TV: ESPN
Time: 8:15 p.m. ET
Week 12: San Francisco 49ers vs. New Orleans Saints, November 27, 2022
TV: FOX
Time: 4:25 p.m. ET
Week 13: San Francisco 49ers vs. Miami Dolphins, December 4, 2022
TV: FOX
Time: 4:05 p.m. ET
Week 14: San Francisco 49ers vs. Tampa Bay Buccaneers, December 11, 2022
TV: FOX
Time: 4:25 p.m. ET
Week 15: San Francisco 49ers @ Seattle Seahawks, December 15, 2022
TV: Amazon Prime
Time: 8:15 p.m. ET
Week 16: San Francisco 49ers vs. Washington Commanders, December 24, 2022
TV: CBS
Time: 4:05 p.m. ET
Week 17: San Francisco 49ers @ Las Vegas Raiders, January 1, 2023
TV: FOX
Time: 4:05 p.m. ET
Week 18: San Francisco 49ers vs. Arizona Cardinals, January 8, 2023
TV: TBD
Time: TBD
